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The Wave PRO™
An innovative approach to Chronic Stable Angina

A non-invasive heart therapy designed to support patients with CSA, simplify clinical delivery, and better care economics.1

Accessible ECP Therapy for Modern Care

For decades, external counterpulsation (ECP) has offered a non-invasive option for adults with Chronic Stable Angina (CSA) who are no longer candidates for revascularization. Yet legacy ECP systems have remained large, immobile, and difficult to integrate into today’s care environments—limiting patient access and creating workflow challenges for clinics and hospitals.

Wave PROTM

Wave PRO’sTM compact, automated, calf-only design makes ECP therapy more comfortable for patients1, simpler for clinicians, and easier for care systems to deploy at scale—expanding access beyond specialized centers.

A Better Experience for Every User

Patients

  • No surgery, no recovery time
  • May help reduce angina-related discomfort 3
  • Calf only design
  • Quieter, more comfortable experience1
  • Delivered by trained personnel and patient controlled
  • Designed for minimal patient disruption

Clinicians

  • Substantial clinical benefit demonstrated by ECP therapy in over 80% of patients with CSA2
  • Minimal setup
  • Automated treatment delivery
  • Operates using a single fingertip sensor
  • Reduces workflow complexity and hands-on time

Care Systems

  • Portable, capital-efficient and reimbursable
  • Small footprint, no dedicated space
  • Minimal staffing requirement
  • Ideal for outpatient, rehab, and community care
  • Automated delivery enhances efficiency
  • Durable, low-maintenance, fully warrantied

Clinically Validated Performance

Wave PRO was clinically tested under the WAVECRESST clinical trial and was shown to be equivalent to predicate ECP thereapy devices, as well as showing a preference for patient comfort and less set up time with a calf-only design for care providers.1

Aligned With Established ECP Outcomes

ECP therapy has been shown to improve symptoms and functional status in over 80% of patients with drug-refractory chronic stable angina. Wave PRO delivers these therapeutic principles through an accessible, automated platform.2

Findings from the WaveCRESST Clinical Study

Equivalent diastolic augmentation ratio (+0.26 Δ vs predicate; p < 0.0001)1
Non-inferior to predicate ECP devices1
Strong patient preference for Wave PRO’sTM more comfortable design1

Wave Pro required less set up time

This animation shows a diagram of the human circulatory system as leg cuffs massage the lower legs to aid in blood flow back to the heart

How Wave PRO Works

Wave PROTM delivers external counterpulsation therapy through lightweight calf sleeves that inflate and deflate in sequence, synchronized with the heart’s resting phase1
. The system uses fingertip PPG sensing and an automated timing algorithm to ensure each compression occurs at the right moment in the cardiac cycle. This simple, automated process helps support healthy blood flow back to the heart.  The Wave PROTM delivers results without surgery, without recovery time, and with minimal staff involvement.

Key Features

  • Pulse-synchronized compression using fingertip PPG sensing
  • Calf-only sleeves with five chambers for targeted, comfortable therapy
  • Automated timing algorithm
  • Set up in minutes
  • Automated delivery once therapy is underway

Indications & Safety

Intended Use

Wave PROTM   is FDA-cleared for adults with Chronic Stable Angina that is refractory to optimal medical therapy and who are not candidates for revascularization. It is also intended for healthy adults seeking improved circulation and vascular performance.1

Safety

The Wave PROTM is designed to be delivered safely under the supervision of trained healthcare professionals, with established protocols to support patient tolerance and clinical use.

Performance

In the WaveCRESST clinical study, Wave PROTM was well tolerated and demonstrated equivalent diastolic augmentation. Patients found Wave Pro’sTM calf-only design more comfortable.1

Experience the Next Generation of ECP Therapy

Wave PROTM makes clinically validated ECP therapy more accessible for patients and easier to deliver across modern care settings.

Patients

Learn more about the Wave PRO

Clinicians

Review clinical evidence and workflow advantages

Care Systems

Explore operational and financial benefits